Thyroid Hormones, T3 and T4, in the Brain

Thyroid Hormones, T3 and T4, in the Brain

Thyroid hormones (THs) are essential for fetal and post-natal nervous system development and also play an important role in the maintenance of adult brain function. Of the two major THs, T4 (3,5,3',5'-tetraiodo-l-thyronine) is classically viewed as an pro-hormone that must be converted to T3 (3,5,3'-tri-iodo-l-thyronine) via tissue-level deiodinases for biological activity. THs primarily mediat...

Thyroid hormones T3 and T4 and their relationship with fibrinolysis variables

A Study of Thyroid Hormones (t3, T4 & Tsh) in Patients of Depression

In this study, 32 unmedicated patients of unipolar depression were included and blood samples were analysed for T(3), T(4) and TSH. These were compared with age and sex matched controls. Subnormal T(3) and T(4) levels in 90.6% and 9.3% respectively and an increase of TSH levels in 18.7% of the total patients was observed in this study. The patients were classified into mild, moderate and severe...

Synthesis of Silver Nano-particles by Electrochemical Method and the Effects on the Serum Levels of Thyroid Hormones (T3, T4) in Adult Male Rats

Background: Silver nano-particles have anti-fungal properties. In the present study, silver nano-particles were synthesized by electrochemical method and its effects on the serum levels ofT3 and T4 hormones were investigated in adult male rats. Methods: In this experimental study, 28 adult male Wistar rats weighing approximately 180-220g were divided into 4 groups of 7 rats. The control grou...

Thyroid hormones in the elderly sick: "T4 euthyroidism".

Thyroid function and serum levels of triiodothyronine (T3) and thyroxine (T4) were investigated in 79 euthyroid geriatric patients. Of the 59 inpatients and 20 outpatients 35 (59%) and 2, respectively, had low T3 levels. In contrast, 7 (12%) and 6 (30%), respectively, had raised T4 levels. Two further patients were excluded from the study because of raised levels of thyroid-stimulating hormone....